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[DOI] [PMC free article] [PubMed] [Google Scholar] 117.Darsalia V., Johansen O.E., Lietzau G., Nyström T., Klein T., Patrone C
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We observed a pronounced vehicle-corrected weight loss of 15.2% in the group treated with GLP-1–MK-801 compared with 3.5% in the group treated with the parent GLP-1 analogue after 9 days of treatment, underscoring that the weight-lowering efficacy of the conjugate is intact in the absence of functional MC4R signalling (Fig
